Are you low on fluid? Bone & Joint Knee Osteoarthritis: Early Signs, Causes, Diagnosis, Treatment Knee Exercises for Arthritis Osteoarthritis Nature Reviews Disease Primers Knee pain is often caused by more than just tiredness. It usually stems from cartilage wear, lack of joint lubrication, or chronic inflammation. When the natural fluids in your joints decrease, movement How to Boost Synovial Fluid and Support Healthy Joints