Espree Flea & Tick SprayReady to Use Water Based Formula. Kills Fleas & Ticks on Contact on Dogs. Will Keep on Killing for Up to 14 Days on Dogs. Directions: For Use on Dogs: Hold the spray nozzle about 812 inches from pet. Start spraying the animal at the tail, making sure to spray the entire coat including the legs, tail and underbody area. With your hand, fluff the hair against the way it normally lies to ensure that the spray penetrates through the coat to the skin.